New Main Street innovation hub kicks off three-month program with three health and tech-focused companies
WORCESTER—A new chapter in Central Massachusetts’ innovation economy officially opened this month as Auxilium Worcester launched its first accelerator cohort inside a newly renovated space at 311 Main St.
The program welcomed three high-potential startups — Akeyna, Splice Histology, and MiComp Solutions — each receiving a $250,000 investment and full access to mentorship, programming, and workspace in the city’s growing entrepreneurship hub.
The launch marks a milestone for Auxilium, a dual-track startup support organization that will also open a 12-month Innovation Studio later this year. Both programs are backed by Rucker Investments and designed to strengthen Worcester’s position as a startup destination.
“This first class of companies reflects the type of innovation we’re here to champion — technologies that are advancing healthcare, improving operational efficiency, and applying AI to solve real-world problems,” said Zak Dutton, executive director of Auxilium Worcester, in a statement. “These founders are all connected to this region, and we’re proud to support their growth right here in downtown Worcester.”
The accelerator, which runs for three months, is operating out of a newly completed 2,300-square-foot suite that includes co-working areas, private offices, a conference room, and kitchen. Phase Two of the facility is slated to open this fall, bringing Auxilium’s total footprint to 14,000 square feet.
The inaugural startup cohort includes Akeyna, Splice Histology, and MiComp Solutions, each tackling critical challenges in healthcare and technology. Akeyna, co-founded by CEO Karen Cronholm, has developed a patented smart needle for aesthetic medicine that detects blood vessels in real time to prevent severe complications during dermal filler injections.
Splice Histology, founded by Worcester native Thomas Schofield, is modernizing pathology workflows by offering slide preparation and digitization services, addressing workforce shortages in the field through automation. Meanwhile, MiComp Solutions, led by CEO Keith Ledoux, provides a digital platform for healthcare payers and brokers that streamlines compliance, licensing, and receivables management using AI-powered insights. All three companies have strong ties to the region and plan to expand their local presence.
From blueprint to breakthrough
The Worcester Guardian first reported on Auxilium’s plans in February, when Dutton described the accelerator as part of a larger effort to create a more connected and resource-rich startup ecosystem across New England. At the time, construction was still underway, and a regional partnership with Rhode Island-based RIHub had just been announced.
“We are creating a stronger, more connected startup ecosystem that will give entrepreneurs a better shot at success,” Dutton told the Guardian. He said the collaboration would help startups navigate common challenges like access to capital, mentorship gaps, and siloed networks.
Auxilium’s Innovation Studio — scheduled to open in Fall 2025 — will complement the accelerator with year-long support for early-stage ventures, offering access to professional services and additional funding.
With its doors now open and investments in motion, Auxilium aims to position Worcester as a magnet for mission-driven startups — and a launchpad for scalable innovation.
More information is available at www.auxiliumworcester.com.
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